*drum roll* Check out Harry’s paper that just came out in eLife! The title of the paper is: Signaling pathways as linear transmitters. Also check out an accompanying Insight article by Steven Andrews, Roger Brent, and Gabor Balazsi. We are so proud of this paper, so much work went into it. The peer-review process was tough, but it really made the paper better in the end. So thank you to the editor and reviewers at eLife who kindly took their time to critique the paper!
Noah wrote an opinion piece for Current Opinion in Biotechnology, There is (still) plenty of room at the bottom. Inspired by Feynman’s lecture 60 years ago, Noah argues that even as the field moves forward to analyze more and more complex networks comprised of many molecules, there are still many fascinating computations to be discovered within the molecules, and that understanding these computations may have interesting ramifications.
Welcome, Lev Tsypin! Lev is rotating in the lab this quarter. He is exploring several fun ideas for projects, some of which involve possibly expanding the organismal ecosystem in the lab. Check out Lev posing with an old microscope from Seymour Benzer’s lab.
Lea is promoted to Professor of Biology. Props to everyone, it is a recognition of our work together.
Congratulations, Noah! Noah will join Johan Paulsson’s lab at the Department of Systems Biology, Harvard Medical School as a postdoc. What great news! But of course, he has to graduate first.
The lab has welcomed many young trainees over these years. It is wonderful to hear their updates, and cherish their adventures. Here are some updates we’ve received so far: Beatriz Aleman graduated from high school and is now at UC Berkeley. Isabella Boyle is at University of Chicago, and Ivan Schmidt will start there soon, too. Paola Benefo will join David’s lab at UC Davis as a research technician. William Yuan is now pursuing PhD in Biological Sciences at Harvard. And Bryan Ryba is in his third year pursuing MD/PhD at UCSD. We hope they are all having fun.
Many congratulations to David! David will start as a junior faculty in UC Davis later this year. Big, awesome milestone, congratulations again!
Congratulations Michael on receiving the Miller Research Fellowship from the Miller Institute at UC Berkeley! It is very, very well deserved. Now he just needs to graduate.
Check out our recent paper in collaboration with the Sternberg and Gradinaru labs, on the discovery that jellyfish show a sleep-like state. Props to the first authors Michael Abrams, Ravi Nath, and Claire Bedbrook! As well as Ty Basinger who helped with setting up the experiments, Justin Bois who gave critical help with developing the computational methods, and David Prober who gave important insights and discussion on the experiments.
Our Big Picture Science interview is featured in NSF Science360 Radio. Check it out!
The beta-catenin paper is officially online! Congratulations Kibeom, Jay, Tom, Andrew, and Harry for the excellent work. Also an author is Bryan Ryba, who helped us with the project a couple of summers as SURF and Amgen fellow. Check out the paper, where we describe a novel cis-regulatory element in the Wnt pathway and a novel role for beta-catenin acting as a signal and a feedforward sensor: Two-Element Transcriptional Regulation in the Canonical Wnt Pathway.
We dedicate the paper to the late Eric Davidson, who had many suggestions for the project, and whose presence we deeply miss.
Andrew leaves the lab to join the biology graduate program at Northwestern. Good luck Andrew, it was so much fun having you in the lab, visit us when you come home.