See commentaries on our work:
Signaling motifs and Weber’s Law, James E. Ferrell, Molecular Cell 36 (5), 724-727, 2009
It’s All Relative, Nancy R. Gough, Science Signaling 2 (101), ec397, 2009
Signalling: Sensing a change, Tanita Casci, Nature Reviews Genetics 11, 92-93, 2010
Evidence that fold change, not absolute level, of b-catenin dictates Wnt signalling
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